https://www.sciencedaily.com/releases/2019/11/191121121730.htm
New mechanism of neurodegeneration
Date:
November 21, 2019
Source:
VIB (the Flanders Institute for Biotechnology)
Summary:
Charcot-Marie-Tooth disease (CMT) is an inherited neurodegenerative condition that affects 1 in 2500 individuals. Currently, however, it is still lacking effective treatment options. New research has demonstrated that a class of cytoplasmic enzymes called tRNA synthetases can cause CMT by interfering with the gene transcription in the nucleus.
