Observational

https://clinicaltrials.gov/ct2/show/NCT03782883

The Impact of Charcot-Marie-Tooth Disease in the Real World

Study Type : Observational [Patient Registry] Estimated Enrollment : 2000 participants
Observational Model: Ecologic or Community
Time Perspective: Prospective
Target Follow-Up Duration: 30 Months
Official Title: The Impact of Charcot-Marie-Tooth Disease in the Real World
Actual Study Start Date : October 9, 2018
Estimated Primary Completion Date : April 9, 2021
Estimated Study Completion Date : April 9, 2021

https://clinicaltrials.gov/ct2/show/NCT03966287

Analysis of Pain and Quality of Life in Patients With Charcot-Marie-Tooth Neuropathy (CMT)

Study Type : Observational
Estimated Enrollment : 200 participants
Observational Model: Cohort
Time Perspective: Retrospective
Official Title: Analysis of Pain and Quality of Life in Patients With Charcot-Marie-Tooth Neuropathy (CMT)
Actual Study Start Date : June 3, 2019
Estimated Primary Completion Date : November 30, 2019
Estimated Study Completion Date : December 31, 2019

https://clinicaltrials.gov/ct2/show/NCT04010188

Study Type : Observational [Patient Registry] Estimated Enrollment : 500 participants
Observational Model: Cohort
Time Perspective: Prospective
Target Follow-Up Duration: 20 Years
Official Title: A Registered Observational Cohort Study of Charcot-Marie-Tooth Disease
Actual Study Start Date : July 1, 2019
Estimated Primary Completion Date : December 31, 2039
Estimated Study Completion Date : December 31, 2049

https://clinicaltrials.gov/ct2/show/NCT01193088?cond=charcot-marie-tooth&rank=15

Genetics of Charcot Marie Tooth (CMT) – Modifiers of CMT1A, New Causes of CMT2 (INC-6602)

Study Description

Brief Summary:
This project includes two projects. One is looking for new genes that cause Charcot Marie Tooth disease (CMT). The other is looking for genes that do not cause CMT, but may modify the symptoms a person has.

Condition or disease
Charcot-Marie-Tooth Disease, Type Ia (Disorder)
HMSN

Detailed Description:
This project is to understand modifier genes and how they influence the severity of disease expression, along with identifying new forms of CMT which have not been genetically determined. Subjects who are eligible will either have CMT type 1A (CMT1A) or an unknown form of CMT. Blood will be drawn and sent to the University of Miami where they receive the coded sample and process it through exome sequencing. Subjects will be told that this is optional.

Study Design
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Study Type : Observational
Estimated Enrollment : 1050 participants
Observational Model: Cohort
Time Perspective: Prospective
Official Title: Genetics of Charcot Marie Tooth Disease (CMT) – Modifiers of CMT1A, New Causes of CMT
Actual Study Start Date : April 2010
Estimated Primary Completion Date : December 2019
Estimated Study Completion Date : December 2019